Curcugen is a dispersible, 98.5% turmeric-based curcuminoids formula, 39-times bioavailability-enhanced to improve plasma absorption and clinical efficacy. A next-generation curcuminoids formula, Curcugen is synergized by numerous turmeric-native actives, is food and beverage friendly, has a pending self-affirmed GRAS assessment, and is uniformly compliant to meet regulatory standards in markets across the globe.
First Food-Matrix / Oleoresin-Based Curcumin BIOAVAILABLE | DISPERSIBLE | PALATABLE
Curcuminoids, turmeric essential oils and resins are naturally housed within the turmeric oleoresin. They are exclusively represented in Curcugen and complemented by a diverse spectrum of other turmeric native compounds. Curcugen’s full-spectrum profile benefits from the strategic and patent-protected application of safe, food-grade solvents and precipitants.
Curcugen is the only oleoresin-sourced turmeric active on the market to generate its absorption benefit from the dispersion power found in a previously ignored turmeric native – ‘polar’ resins.
Curcugen uniquely delivers the same ratio of curcuminoid analogues – curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC) – as found in the turmeric rhizome in its food state, or as its primary derivative, the oleoresin. While Curcugen is concentrated to a 50% standard of curcuminoids, it is not hyper-purified, as is common with other curcuminoid formulations. Therein, Curcugen retains a closely matched ratio of these cousin-molecules to what is natural, and found most familiarly in food.
Human Bioavailability studies
In an 18-subject, cross-over pharmacokinetics study over 24-hours, Curcugen, at 2000 mg of curcuminoids equivalents enhanced Free-curcumin bioavailability by 39X that of placebo, and proved 52.5-times more bioavailable for Total Curcuminoids than placebo.
Curcugen is one of the first curcuminoids formulas to prove an increase in the bioavailability of endogenously-produced tetrahydrocurcumin (THC). THC is thought to be a more potent antioxidant than curcumin, although curcuminoid analogues appear to still offer more potent inflammatory signal modulation than THC. Curcugen enhanced total THC bioavailability by 31X over placebo.
Human Efficacy studies
Curcugen’s efficacy is backed by several clinical studies in the dosage range of 500 – 1000 mg/day that are either still in progress or under peer review. Please contact our team for more details.
Curcugen is a suitable for a variety of formulations – traditional and novel food and beverage formats alike. Curcugen is palate-friendly – requiring minimal flavoring and no masking, free flowing, highly dispersible and very stable. Many formulation concepts for Curcugen have been explored, some of which include: