Curene®

Total Turmeric

PRODUCT HIGHLIGHTS

  • Once daily dose: 500 mg
  • World’s first formulation from whole turmeric extract (>20% total Curcuminoids)
  • 113x bioavailable for free Curcumin
  • 51% reduction in total WOMAC score of knee osteoarthritis 
  • Based on Patented Aqueosome® technology

Bioavailability Studies

A. Animal Study

Animal BA study to compare the oral bioavailability of Curene® and standard curcumin (95%)

In comparative bioavailability study, Curene® was found to be superior to the standard curcumin (95%)  and leading Curcumin formulation.

B. BRAIN TRANSPORT STUDY

Curene® delivers curcumin into brain-Animal Study

Confocal 3 D image of brain section from rat supplemented with Curene® (Green Fluorescence confirms the presence of curcumin)

C. HUMAN STUDY

Human BA study to compare the oral bioavailability of Curene® and standard curcumin (95%)

Curene® showed 113x higher relative bioavailability than standard Curcuminoids (95%)

Human Clinical Efficacy Studies

In a human clinical efficacy study (n=50), single dose of Curene® reduced joint pain, stiffness and improved Physical functioning significantly in Osteoarthritis Patients as assessed by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score. This study also confirmed the long-term safety of Curene®.

  Curene® Placebo
Reduction in Total WOMAC Score 51.3% 17.6%
Reduction in Pain Score 48.0% 14.7%
Reduction in Stiffness Score 53.1% 20.3%
Improvement in Physical functioning 52.0% 18.1%
Reduction in Visual Analogue Score (VAS) 47.9% 15.0%

Safety Studies

Curene® is evaluated for safety through animal and human studies.

1. Animal Safety Study:
       Acute oral toxicity study conducted as per OECD guidelines: LD50 was found to be >5000 mg/Kg BW
2. Human Safety studies:
       Safety was evaluated through three human clinical studies: Product was found to be safe

‘These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.’

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